Comprehensive STD Panel Cost Comparison (2026)
Comprehensive STD panels vary more in scope than any other test category on this site. A panel labeled "comprehensive" at one portal may cover 5 infections; at another it covers 10. Price differences often reflect what is included, not just portal markup. This comparison shows what each provider's panel covers alongside price — so you can make an apples-to-apples choice. Prices are from each provider's public website as of May 2026.
Key takeaways
- Jason Health has the lowest-priced panel at $108, but it covers 5 infections (the $18 fee is already included in the listed price).
- HealthLabs offers a 10-infection panel at $139 — broader scope for modestly more money.
- LabReqs ($289) and DirectLabs ($319) are among the most expensive; LabReqs covers 6 infections for that price.
- These panels are not identical — compare what each covers, not just the price.
Our recommendation
- HealthLabs Comprehensive STD Panel (10 tests, $139) offers the broadest infection coverage at the lowest price — testing twice as many infections as the Jason Health 5-test panel for only $31 more.
- Jason Health Full 8 Test STD Panel ($123 all-in, $18 fee included) is the next-best value if the 10 infections HealthLabs covers exceed your needs — it covers 8 infections including chlamydia, gonorrhea, syphilis, hepatitis B, hepatitis A, hepatitis C, and HIV.
- LabReqs Comprehensive ($289) covers 6 infections at more than twice the HealthLabs price — it is not the best-value option for STD testing based on price and scope alone.
- Regardless of portal, compare the specific infections listed for the panel you are considering. These panels are not identical.
Why: HealthLabs 10-test $139 vs. Jason Health 8-test $123 all-in vs. LabReqs 6-infection $289. Scope and price per infection both favor HealthLabs and Jason Health.
Why panels differ in scope
STD panels differ meaningfully in how many infections they cover. A "comprehensive" label at one portal does not equal "comprehensive" at another. Key variables: HIV type (4th-gen Ag/Ab vs. RNA early detection), whether hepatitis C and herpes (HSV 1 and 2) are included, and whether blood only or blood plus urine is collected. See the STD Testing Basics Guide for details on each infection type.
Price and scope comparison table
Sorted by listed price, cheapest-first. Because panel scopes differ, this table shows infections covered for each. These panels are not identical — compare what each covers, not just the price.
| Provider | Listed price | Fees note | Est. total | Tests included | Infections covered |
|---|---|---|---|---|---|
| Jason Health (Full 5 Test) | $108.00 | $18 lab order fee included in listed price | ~$108 | 5 tests | Chlamydia/Gonorrhea (RNA), Syphilis (RPR), HIV-1/2 Antigen and Antibodies |
| Jason Health (Full 8 Test) | $123.00 | $18 lab order fee included in listed price | ~$123 | 8 tests | Chlamydia/Gonorrhea, Syphilis (RPR), Hepatitis B Surface Antigen, Hepatitis A IgM, Hepatitis C Antibody, HIV-1/2 |
| HealthLabs | $139.00 | None stated | ~$139 | 10 tests | 10 most common STIs (specific list available on their site; covers chlamydia, gonorrhea, syphilis, HIV, herpes, and others) |
| RequestATest | $209 (LabCorp) / $215 (Quest) | None stated | ~$209–$215 | ~4 tests | HIV Antigen/Antibody, Hepatitis B Panel, Hepatitis C, Herpes 1&2 |
| Accesa Labs | $219.00 | None stated | ~$219 | Panel | Comprehensive screening for common STDs in both blood and urine (specific list on their site) |
| LabReqs | $289.00 | None stated | ~$289 | 6 infections | Gonorrhea, Syphilis, HIV, Herpes 1 & 2, Hepatitis B, Hepatitis C |
| DirectLabs | $319.00 | None stated | ~$319 | 6 infections | Chlamydia, Gonorrhea, Herpes, Syphilis, Hepatitis A (IgM), Hepatitis B (IgM) |
Prices gathered from each provider's public website, May 2026; confirm current totals before ordering.
Important note on scope differences: The Jason Health 5-test panel at $108 covers chlamydia, gonorrhea, syphilis, and HIV — it does not include herpes or hepatitis. The Jason Health 8-test panel at $123 all-in adds hepatitis B, hepatitis A, and hepatitis C for $15 more. The HealthLabs 10-test panel at $139 covers the broadest range of infections at the lowest cost-per-infection. LabReqs ($289) and DirectLabs ($319) are substantially more expensive for fewer infections than HealthLabs. If broad coverage is the goal, HealthLabs' 10-test panel offers the strongest value per dollar in this comparison.
These panels are not identical — compare what each covers, not just the price.
Fees that affect true totals
As with titer tests, Jason Health's listed price of $108 already includes the $18 lab order fee — there are no additional charges at checkout. Other providers in this comparison do not state additional fees for their STD panels.
Related comparisons
Frequently asked questions
Which STD panel is cheapest?
Jason Health offers the lowest listed price at $108 for a 5-test panel (Chlamydia/Gonorrhea, Syphilis, HIV-1/2) and $123 for a Full 8 Test panel (adds Hepatitis A, B, C). HealthLabs offers a 10-test panel at $139 — covering the broadest range for $31 more than the 8-test panel. The "cheapest" choice depends on what coverage you need.
Why is LabReqs so much more expensive than Jason Health for STD testing?
LabReqs charges $289 for a 6-infection panel, while Jason Health charges $108 for 5 infections. The pricing difference is primarily a reflection of portal pricing decisions, not test quality. Both use major national lab networks. If STD testing is your goal and budget matters, Jason Health and HealthLabs are substantially cheaper for equivalent or broader coverage.
Does the STD panel include HIV?
It depends on the panel. Jason Health's 5-test panel includes HIV-1/2 Antigen and Antibodies. HealthLabs' 10-test panel includes HIV. RequestATest's Essential panel includes HIV Antigen/Antibody. LabReqs' panel includes HIV. DirectLabs' comprehensive panel does not explicitly list HIV — confirm before purchasing. Always check the specific infections listed for each panel.
What infections does CDC recommend screening for?
CDC recommendations vary by age, sex, and risk factors. The core recommendations include: chlamydia and gonorrhea (annually for sexually active women under 25 and older women at risk); syphilis (for those at increased risk); hepatitis B (for adults not previously vaccinated or screened); hepatitis C (at least once for all adults 18–79); and HIV (at least once for adults 15–65, more frequently for those at higher risk). Consult CDC guidelines or a healthcare provider for personalized screening recommendations.
Sources
- CDC — STD Screening Recommendations — https://www.cdc.gov/std/prevention/screeningreccs.htm
- CDC — Vaccination Technical Instructions for Civil Surgeons (Form I-693) — https://www.cdc.gov/immigrant-refugee-health/hcp/civil-surgeons/vaccination.html
- Provider pricing sourced from each provider's public website, May 2026.