Heart & Cardiac Blood Test Cost Comparison: Lipid, hs-CRP, Homocysteine (2026)
Cardiovascular risk assessment often involves three complementary blood tests: the lipid panel (cholesterol), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. Online portals charge very different prices for each of these tests, and the cheapest provider varies by test. This page gives honest, side-by-side pricing for all three cardiac markers — with checkout fees included — so you can compare what you'd actually pay.
Key takeaways
- For a lipid panel: LabReqs ($25) is now the cheapest listed option, ahead of Jason Health ($28) and HealthLabs ($29).
- For hs-CRP: Jason Health ($38) is the lowest listed price; LabReqs is second at $39.
- For homocysteine: Ulta Lab Tests lists $49.90 (plus $12.95 fee = ~$62.85 total); LabReqs is $61 all-in — making LabReqs the better value here.
- LabReqs' Heart Health Panel ($129) bundles all three tests and compares favorably to building them individually from different portals.
Three cardiac markers explained
These three tests each add something distinct to a cardiovascular risk picture:
- Lipid panel — measures total cholesterol, HDL, LDL, and triglycerides. The foundational cardiovascular screening test.
- hs-CRP (high-sensitivity C-reactive protein) — a marker of systemic inflammation. Elevated levels are associated with higher heart disease risk even when cholesterol levels appear normal. Used to refine cardiovascular risk stratification.
- Homocysteine — an amino acid that, at elevated levels, is linked to increased risk of cardiovascular disease, stroke, and venous thrombosis. Also a marker for vitamin B12 and folate status.
None of these tests is diagnostic on its own. A healthcare provider interprets them together with your medical history, blood pressure, family history, and other factors. See the Heart & Cardiac Testing hub for a broader explanation of how these markers are used clinically.
Lipid panel prices
The standard lipid panel is the same test across all portals — total cholesterol, HDL, LDL, and triglycerides. Sorted cheapest-first by listed price.
| Provider | Listed price | Fees note | Est. total | What's included |
|---|---|---|---|---|
| LabReqs | $25.00 | None stated | ~$25 | Total cholesterol, HDL, LDL, and triglycerides |
| Jason Health | $28.00 | $18 lab fee included in listed price | ~$28 | Total cholesterol, HDL, LDL, triglycerides, cholesterol/HDL ratio, non-HDL-C |
| HealthLabs | $29.00 | None stated | ~$29 | Cholesterol and triglyceride levels |
| Accesa Labs | $49.00 | None stated | ~$49 | Total Cholesterol, HDL, LDL, Triglycerides |
See lipid panel cost comparison for the full breakdown including Ulta Lab Tests' combined panel note.
hs-CRP (high-sensitivity C-reactive protein) prices
The hs-CRP test uses a highly sensitive immunoassay to detect low levels of C-reactive protein. All portals below test the same marker. Sorted cheapest-first by listed price.
| Provider | Listed price | Fees note | Est. total | What's included |
|---|---|---|---|---|
| Jason Health | $38.00 | $18 lab fee included in listed price | ~$38 | High-sensitivity CRP for cardiovascular disease risk prediction |
| LabReqs | $39.00 | None stated | ~$39 | High-sensitivity C-reactive protein for heart inflammation risk |
| Walk-In Lab | $41.00 | None stated | ~$41 | Cardiac risk assessment, inflammation markers |
| Ulta Lab Tests | $48.90 | +$12.95 lab order fee at checkout | ~$61.85 | High-sensitivity C-reactive protein (inflammatory risk) |
| Accesa Labs | $59.00 | None stated | ~$59 | hs-CRP blood level for inflammation and cardiac risk |
| RequestATest | $59.00 | None stated | ~$59 | CRP High Sensitivity, cardiac CRP biomarker |
| HealthLabs | $79.00 | None stated | ~$79 | Hidden inflammation linked to heart disease |
Prices from each provider's public website, May 2026. Confirm current totals before ordering.
Homocysteine prices
Homocysteine tests are offered by fewer portals. Sorted cheapest-first by effective total.
| Provider | Listed price | Fees note | Est. total | What's included |
|---|---|---|---|---|
| Ulta Lab Tests | $49.90 | +$12.95 lab order fee at checkout | ~$62.85 | Homocysteine level for cardiovascular and stroke risk |
| LabReqs | $61.00 | None stated | ~$61 | Homocysteine for cardiovascular and vitamin-related risk |
| HealthLabs | $68.00 | None stated | ~$68 | Amino acid to assess cardiovascular and nutritional risk |
| RequestATest | $69.00 | None stated | ~$69 | Homocysteine to assess risk for heart attack or stroke |
Note: Ulta Lab Tests' listed $49.90 becomes approximately $62.85 after the $12.95 checkout fee — making LabReqs at $61 the better total value for homocysteine alone.
Bundle vs. individual ordering
If you need all three tests — lipid panel, hs-CRP, and homocysteine — consider whether a bundle saves money over ordering separately:
- LabReqs Heart Health Panel ($129): covers lipid panel + hs-CRP + homocysteine. Using LabReqs individually: $25 + $39 + $61 = $125. The bundle is a slight $4 premium for the convenience of a single order and single lab network.
- Cheapest individual sourcing: LabReqs lipid ($25) + Jason Health hs-CRP ($38) + LabReqs homocysteine ($61) = $124. Requires two separate orders (two different lab networks).
- DirectLabs Cardiac Risk Profile ($259): Includes advanced lipid panel (Cardio IQ), CBC, hs-CRP, Vitamin D, HbA1c, and homocysteine — a much broader panel for those wanting a comprehensive cardiac workup.
These panels are not identical — compare what each covers, not just the price.
Related comparisons
- Lipid panel (cholesterol) cost comparison
- Heart & Cardiac Testing: Tests, Prices, and Risk Markers
- Diabetes Test Cost Comparison (A1c, Glucose, Insulin)
- Lab Tests Without Insurance
- Full provider comparison
Frequently asked questions
What is the cheapest hs-CRP test online?
Jason Health lists the lowest hs-CRP price at $38, with the $18 lab order fee already included in the listed price — making it the all-in lowest cost option. LabReqs is a close second at $39 with no additional fee stated. Both use major national lab networks (Quest and LabCorp respectively).
Should I get hs-CRP and lipid panel together?
Many cardiologists and prevention-focused clinicians order both together because they measure different aspects of cardiovascular risk — cholesterol levels vs. inflammatory burden. Whether to order both depends on your risk profile and healthcare provider guidance. If you need both, LabReqs' Heart Health Panel ($129) may be more economical than ordering separately.
Why is HealthLabs so much more expensive for hs-CRP?
HealthLabs lists hs-CRP at $79 — significantly higher than Jason Health ($38) or LabReqs ($39). Portal pricing reflects each company's fee structure, not differences in test quality. The underlying lab test uses the same methodology at Quest Diagnostics regardless of which portal you order through.
What does a high homocysteine level mean?
Elevated homocysteine (hyperhomocysteinemia) has been associated with increased cardiovascular and cerebrovascular disease risk. It can also indicate low vitamin B12, B6, or folate levels. Interpretation depends on your overall health profile — consult your healthcare provider for guidance on results.
Sources
- MedlinePlus — C-Reactive Protein (CRP) Test — https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/
- MedlinePlus — Homocysteine — https://medlineplus.gov/lab-tests/homocysteine-test/
- Provider pricing sourced from each provider's public website, May 2026: Jason Health, HealthLabs, LabReqs, Accesa Labs, Walk-In Lab, RequestATest, Ulta Lab Tests.